Description
Finasteride – a highly effective generic drugs, whose action is directed to the treatment of baldness (alopecia) androgen-type males This type of alopecia areata is characterized by parietal and frontal parts Stimulation of hair growth is due to the stabilization of hormone levels.. . As a result, the metabolic processes are restored inside the follicles (hair follicles), normalized their eating and cell division.
For generics group include pharmaceuticals, the chemical composition and the active base which expired patent restrictions. According to the legal base, after the end of this period, allowed the mass production of off-patent drug.According to the therapeutic effect and the composition of generics do not differ from the primary analog (drug development company). For the price of the original production of Finasteride is much more expensive than their generic.
Description of the preparation
The drug has been certified in many countries around the world, including in Russia. Propecia, which can be bought in Moscow, represented by generic production of several pharmaceutical companies (India and USA).
Initially, the drug was developed as a means to stimulate and restore the secretory function of the prostate gland. The therapeutic effect of Propecia on the prostate due to the normalization of the levels of DHT.
Testosterone can take a more active form dihydrotestosterone . With the increased level of education of the androgen dihydrotestosterone bind multiple lesions of the prostate cells, its hypertrophy (enlargement) and hyperplasia (overgrowth of the secretory tissue). Also under the influence of this hormone in the body there is the development of cancer processes (up to an adenoma).
Elevated levels of dihydrotestosterone leads not only to prostate lesion. As a result, it suffered hypersecretion and other tissues. Most often it is the hair follicles in the scalp.
In clinical trials it has been found that in addition to the restoration activity of the prostate drug has another therapeutic effect. It turned out that generic Propecia stimulates growth and normalizes the vital functions of the hair follicles. Under the influence of the drug improves the metabolic processes within the hair follicles. There is a full or partial recovery of the hair cells, the activity of which has been changed over the degenerative processes.
Finasteride also allows the drug not only normalize metabolic processes within the degenerating cells. To provide them with a therapeutic effect on the male body is a stimulant for the development of new hair follicles.
The ability to use Finasteride baldness fully revealed only after admission to the sale. Carrying out a statistical study found that Finasteride tablets have helped to get rid of androgenic alopecia about 80% of all men surveyed.
Operating principle
The ability of the drug stimulyativno affect the recovery of hair is due to its composition of finasteride. 1 mg of the substance capable of during the day completely deactivate and neutralize the pathologic effects of DHT. However, provided that this androgen is produced in the male excess. Finasteride neutralize the production of DHT by inhibiting the action of the enzyme reductase.
The process of forming a more active form of testosterone passes under the action of the enzyme reductase. With reduced secretion inhibitor of the enzyme. Inhibitors are substances that can slow down, prevent or completely neutralize during a chemical reaction. They have a highly directional action . Part of the drug finasteride inhibitor inhibitsproduction of a reductase enzyme, which occurs under the influence of the conversion of testosterone to dihydrotestosterone (more active form of the hormone).
Mode of application
Before you start treatment carefully read the instruction finasteride and description of its contraindications The average daily dose of the drug for the treatment of alopecia – 1 mg Course duration: from 3 months to six months But before you buy Propecia and start receiving,.. should consult a physician. The effectiveness oftreatment can be assessed only after a few months of receiving.
Before the course should visit an endocrinologist. In some cases, the doctor may prescribe additional laboratory studies to examine in detail the patient’s hormonal background. Possible adjustment of the dosage and timing of receiving generic. Therefore, the duration of the course and the cost of Finasteride may be calculated for each patient individually .
Finasteride is allowed to use the drug in transplant (transplant) hair follicles. In this case, its operation will be directed to the normalization of testosterone to physiological. What it is one of the conditions for normal engraftment of donor hair follicles.
Side effects
Finasteride can cause side effects These include. :
· The reduction of sexual libido.
· Reducing the volume of ejaculate.
· Temporary (partial) impotence.
· Allergic reactions.
Contraindications
The drug is contraindicated for the reception of patients suffering from the following diseases:
· Allergy to one of the components.
· Diseases of the endocrine system.
· Hepatic insufficiency.
· Prostatitis caused by urogenital infection.
· uropathy obstructive type.
Finasteride that is a specific inhibitor of 5a-reductase. Proscar is the enzyme responsible for converting testosterone into DHT (dihydrotestosterone). The substance can efficiently reduce the serum concentration of DHT, therefore Proscar minimizes the unwanted androgenic effects that result from its presence. The effect of finasteride is quite rapid, suppressing serum DHT concentrations as much as 65% within 24 hours after taking a single 1mg tablet. Medically, Finasteride has been marketed to treat two specific conditions. The first release of Finasteride in the U.S. was under the brand name of Proscar. It was made for use by patients with benign prostate hyperplasia (prostate enlargement). More recently (December 1997), Finasteride was approved for use as an anti-balding medication. We now have the additional brand name Propecia. Propecia is the same drug but the tablet contains only 115 of the Proscar dosage. Scientists have long believed that DHT was the main culprit in many cases of male hair loss (along with genetic factors), so there was little doubt after the release of Proscar that Finasteride would eventually be used for this purpose. It has provided what many feel is a breakthrough for men with hair-loss problems.
