Instructions for use
INN: TESTOSTERONE
The international non-proprietary name of the active ingredient – is basic information about the drug. The fact that, as a rule, drugs with the same active ingredient are produced under various trade names, that is in fact one and the same medicine, but produced by different firms. INN It allows professionals to navigate in a large quantity of drugs available in the pharmaceutical market.
Drug Name in English: ANDRIOL TC
Manufacturer: ORGANON N.V. produced CATALENT FRANCE BEINHEIM S.A.
Composition: Soft gelatin capsules, oval, size ?6, orange, shiny, with napisyu “ORG DV3” white; contents of capsules – transparent oily yellow liquid. 1 caps. testosterone undecanoate 40 mg. 
Other ingredients: propylene glycol monolaurate, srednetsepochnye triglycerides, lecithin, castor oil, glycerol, gelatin, colorant sunset yellow (E110, FD & C Yellow ?6).
10 pieces. – Blisters (1) – foil sachet (3) – packs cardboard.
10 pieces. – Blisters (1) – foil sachets (6) – packs cardboard.
10 pieces. – Blisters (1) – foil sachets (12) – packs cardboard.
Pharmacological group: Androgenic
Pharmachologic effect:
Testosterone – is an endogenous hormone, necessary for the normal development of male sex organs and secondary sex characteristics, in order to maintain the normal function of the testes, prostate and seminal vesicles, the maintenance of libido and potency. Use of the drug for the treatment of hypogonadism in men results in a clinically significant increase in the plasma concentration of testosterone, dihydrotestosterone, and androstenedione and a reduction of sex hormone binding globulin (SHBG). In males with primary (hypergonadotrophic) hypogonadism use of the drug leads to normalization of gonadotropin concentrations.
Pharmacokinetics:
After oral administration of testosterone undecanoate significant part together with a lipophilic solvent absorbed in the small intestine and enters the lymphatic system thus avoiding first pass through the liver. After absorption of testosterone undecanoate partially reduced to form dihydrotestosterone undecanoate. From the lymphatic system, it enters into the plasma. In plasma and tissues as a result of hydrolysis of testosterone undecanoate and ditdrotestosterona undecanoate released natural male sex hormones testosterone and dihydrotestosterone.
A single dose of 80 -160 mg TK Andriol leads to a clinically significant increase in total plasma concentrations of testosterone, Cmax is approximately 40 nmol / l is reached within 4-5 hours after ingestion. Increased testosterone level is still present, but at least for 8 hours. Shown mainly in the urine as conjugates (etioholanolon and androsterone). read more
It describes how the medicine gets into the body, passes through the tissue; It can accumulate in them and how much is discharged to the outside.
Dosage and administration: Dose picked individually, depending on the clinical effect.
As a rule, the initial dose is 120-160 mg / day for 2-3 weeks, maintaining dose – 40-120 mg / day.
The drug should be taken with meals, with a little water. The capsules should be swallowed whole without chewing. It is advisable to take half the dose in the morning and half in the evening. If it is an odd number of capsules, the higher the dose should be taken in the morning.
Overdose:
Symptoms: disorders of the gastrointestinal tract.
Treatment: gastric lavage, symptomatic treatment.
Drug Interactions:
While the use of enzyme inducers of microsomal oxidation (barbiturates, rifampicin) may reduce the effectiveness of the drug.
Very important information is not always taken into account when taking medication. If you are taking two or more drugs, they can either weaken or strengthen the effect of each other. In the first case you will not get the expected result of the drug, and the second – run the risk of overdose or poison.
Pregnancy and lactation: Contraindicated during pregnancy and lactation.
Many medications can adversely affect the embryo or fetus and even lead to malformations of the child. Also taken drugs with their mother’s milk into the body baby, and act on it. Therefore, pregnant and nursing women should be treated with great caution in the use of drugs.
Side effect:
In prepubertal boys:
– Precocious puberty;
– Premature closure of growth zones bones;
– Increased frequency of erections and increased penis size.
In men:
– Priapism;
– Increased sexual arousal;
– Oligospermia;
– Reducing the volume of ejaculate.
All patients:
– Sodium and water retention.
Almost all medications have side effects. Typically, this occurs at the maximum medication doses when used in medicine for a long time, while taking multiple medications. Available and idiosyncrasy of a particular substance. It can harm the body, so if the drug causes side effects you have, you have to stop taking it and consult a specialist.
Storage conditions:
The drug should be stored at a temperature of 8-30 ° C and protected from light and out of reach of children. Do not freeze. Shelf life – 3 goda.Ne used after the expiration date.
Never use drugs expired. At best, they will not work, and at worst – will cause harm.
Indications:
Information on what makes Andriol TC:
Hormone replacement therapy in disorders associated with testosterone deficiency:
– Post-castration syndrome;
– Syndrome;
– Hypopituitarism;
– Endocrine impotence;
– Certain forms of infertility associated with the violation of spermatogenesis;
– Menopausal symptoms in women, such as decreased libido and physical activity, deterioration of the general state of health;
– Masculinization in transsexuals.
In addition, testosterone therapy may be indicated for men with osteoporosis caused by androgen deficiency.
Attention! Do not choose their medication using the information in this section. The action of drugs is very individual, and they must appoint only doctor.
Contraindications:
– Hypersensitivity to any components of the preparation;
– Verified or suspected carcinoma of the prostate or breast cancer;
– Pregnancy and lactation.
Precautions: boys in prepubertal avoid premature epiphyseal closure and accelerated puberty; latent or severe heart failure, renal dysfunction, hypertension, epilepsy, migraine (now or in history); benign prostatic hypertrophy.
Special instructions:
In the case of androgenozavisimyh side effects, treatment should be discontinued. After their disappearance should resume treatment with lower doses. Use of the drug can affect the results of certain lab tests.
Never use expired medicines. At best, they will not work, and at worst – will cause harm.
Conditions of supply of pharmacies: The drug prescription. bodybuilding protein shake standing dumbbell side bends supplement for bodybuilding beginner